The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 14, 2017

Filed:

Jan. 09, 2014
Applicants:

Michael Patrick Dillon, San Francisco, CA (US);

Ronald Charles Hawley, Mountain View, CA (US);

LI Chen, Shanghai, CN;

Linchin Feng, Shanghai, CN;

Minmin Yang, Shanghai, CN;

Inventors:

Michael Patrick Dillon, San Francisco, CA (US);

Ronald Charles Hawley, Mountain View, CA (US);

Li Chen, Shanghai, CN;

Linchin Feng, Shanghai, CN;

Minmin Yang, Shanghai, CN;

Assignee:

Hoffmann-La Roche Inc., Little Falls, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 257/04 (2006.01); C07D 498/08 (2006.01); C07D 401/10 (2006.01); C07D 403/10 (2006.01); C07D 403/14 (2006.01); C07D 405/12 (2006.01); C07D 407/10 (2006.01); C07D 413/10 (2006.01); C07D 417/10 (2006.01); C07D 491/10 (2006.01); C07D 241/12 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 403/12 (2006.01); C07D 409/12 (2006.01); C07D 417/12 (2006.01); C07D 471/04 (2006.01); C07D 491/107 (2006.01);
U.S. Cl.
CPC ...
C07D 498/08 (2013.01); C07D 241/12 (2013.01); C07D 257/04 (2013.01); C07D 401/10 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/10 (2013.01); C07D 403/12 (2013.01); C07D 403/14 (2013.01); C07D 405/12 (2013.01); C07D 407/10 (2013.01); C07D 409/12 (2013.01); C07D 413/10 (2013.01); C07D 417/10 (2013.01); C07D 417/12 (2013.01); C07D 471/04 (2013.01); C07D 491/10 (2013.01); C07D 491/107 (2013.01);
Abstract

Compounds of the formula V: or a pharmaceutically acceptable salt thereof, wherein, Ris optionally substituted phenyl, optionally substituted pyridin-2-yl or optionally substituted thienyl, and R, R, R, Rand Rare as defined herein. Also provided are methods of using the compounds for treating diseases associated with the P2Xand/or a P2Xreceptor antagonist and methods of making the compounds.


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