The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 14, 2017
Filed:
Dec. 29, 2015
Applicant:
Recordati Ireland Ltd., Co. Cork OT, IE;
Inventors:
Carlo Riva, Varese, IT;
Carlo De Toma, Milan, IT;
Patrizia Angelico, Sesto S. Giovanni, IT;
Elena Poggesi, Milan, IT;
Davide Graziani, Milan, IT;
Assignee:
RECORDATI IRELAND LTD., , IE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 498/04 (2006.01); A61K 31/424 (2006.01);
U.S. Cl.
CPC ...
C07D 498/04 (2013.01); A61K 31/424 (2013.01);
Abstract
This invention relates to compounds of formula I, their use as allosteric modulators of mGluR5 receptor activity, pharmaceutical compositions containing the same, and methods of using the same as agents for the treatment and/or prevention of neurological and psychiatric disorders associated with glutamate dysfunction, such as schizophrenia or cognitive decline, dementia or cognitive impairment, or other pathologies that can be related directly or indirectly to glutamate dysfunction.