The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 14, 2017

Filed:

Aug. 24, 2012
Applicants:

Jiangao Song, Sunnyvale, CA (US);

Phuongly Pham, San Francisco, CA (US);

Jingyuan MA, Sunnyvale, CA (US);

Aaron Robert Novack, San Jose, CA (US);

Imad Nashashibi, San Jose, CA (US);

David W. G. Wone, Newark, CA (US);

Dong-fang Shi, Fremont, CA (US);

Xin Chen, San Ramon, CA (US);

Inventors:

Jiangao Song, Sunnyvale, CA (US);

Phuongly Pham, San Francisco, CA (US);

Jingyuan Ma, Sunnyvale, CA (US);

Aaron Robert Novack, San Jose, CA (US);

Imad Nashashibi, San Jose, CA (US);

David W. G. Wone, Newark, CA (US);

Dong-Fang Shi, Fremont, CA (US);

Xin Chen, San Ramon, CA (US);

Assignee:

CYMABAY THERAPEUTICS, INC., Hayward, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 307/78 (2006.01); C07D 307/79 (2006.01); C07D 471/04 (2006.01); C07D 473/04 (2006.01); C07D 498/04 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); C07D 473/04 (2013.01); C07D 498/04 (2013.01);
Abstract

The present disclosure relates to compounds that act as agonists of, or otherwise modulate the activity of, GPR131 and to their use in the treatment of various diseases. In particular embodiments, the structure of the compounds is given by Formula I: wherein the variables are as described herein. Related compositions, formulations and methods for the preparation of compounds of formula I are also described.


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