The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 14, 2017

Filed:

Feb. 07, 2014
Applicant:

Heptares Therapeutics Limited, Welwyn Garden, GB;

Inventors:

David Livermore, Cambridge, GB;

Kathryn White, Cambridge, GB;

Miles Congreve, Welwyn Garden, GB;

Giles Brown, Welwyn Garden, GB;

Michael O'Brien, Welwyn Garden, GB;

Assignee:

Heptares Therapeutics Limited, Welwyn Garden, GB;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4523 (2006.01); C07D 401/14 (2006.01); C07D 417/14 (2006.01); C07D 413/14 (2006.01); C07D 409/14 (2006.01); A61K 31/454 (2006.01); A61K 31/4545 (2006.01); A61K 31/506 (2006.01); A61K 31/55 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 417/14 (2013.01); A61K 31/454 (2013.01); A61K 31/4545 (2013.01); A61K 31/506 (2013.01); A61K 31/55 (2013.01); A61K 45/06 (2013.01); C07D 401/14 (2013.01); C07D 409/14 (2013.01); C07D 413/14 (2013.01);
Abstract

The present invention provides muscarinic Mreceptor agonists of formula (I) and pharmaceutically acceptable salts thereof, wherein m, n, p, q, R, Rand Rare as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of diseases such as schizophrenia, Alzheimer's disease and various cognitive disorders as well as in the treatment or alleviation of pain.


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