The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 14, 2017

Filed:

Oct. 13, 2015
Applicant:

Yuhan Corporation, Seoul, KR;

Inventors:

Byung-Chul Suh, Lexington, MA (US);

Paresh Devidas Salgaonkar, Medford, MA (US);

Jaekyoo Lee, North Andover, MA (US);

Jong Sung Koh, Gyeonggi-Do, KR;

Ho-Juhn Song, Andover, MA (US);

In Yong Lee, Belmont, MA (US);

Jaesang Lee, Belmont, MA (US);

Dong Sik Jung, Chungcheongnam-Do, KR;

Jung-Ho Kim, Gyeonggi-Do, KR;

Se-Won Kim, Gyeonggi-Do, KR;

Assignee:

Yuhan Corporation, Seoul, KR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/506 (2006.01); C07D 403/04 (2006.01); C07D 403/14 (2006.01); C07D 409/14 (2006.01); C07D 413/14 (2006.01);
U.S. Cl.
CPC ...
C07D 403/04 (2013.01); C07D 403/14 (2013.01); C07D 409/14 (2013.01); C07D 413/14 (2013.01); A61K 31/506 (2013.01);
Abstract

The present invention provides a new group of protein kinase inhibitors, aminopyrimidine derivatives, and pharmaceutically acceptable salts thereof that are useful for treating cell proliferative disease and disorder such as cancer and immune disease. The present invention provides methods for synthesizing and administering the protein kinase inhibitor compounds. The present invention also provides pharmaceutical formulations comprising at least one of the protein kinase inhibitor compounds together with a pharmaceutically acceptable carrier, diluent or excipient therefore. The invention also provides useful intermediates generated during the syntheses of the aminopyrimidine derivatives.


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