The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 14, 2017
Filed:
Sep. 10, 2013
Applicant:
Reata Pharmaceuticals, Inc., Irving, TX (US);
Inventors:
Christopher F. Bender, Garland, TX (US);
Xin Jiang, Coppell, TX (US);
Eric Anderson, Southlake, TX (US);
Melean Visnick, Irving, TX (US);
Assignee:
REATA PHARMACEUTICALS, INC., Irving, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 255/47 (2006.01); C07J 63/00 (2006.01); C07D 207/08 (2006.01); C07D 207/12 (2006.01); C07D 211/46 (2006.01); C07D 213/75 (2006.01); C07D 233/90 (2006.01); C07D 295/205 (2006.01); C07D 305/08 (2006.01);
U.S. Cl.
CPC ...
C07C 255/47 (2013.01); C07D 207/08 (2013.01); C07D 207/12 (2013.01); C07D 211/46 (2013.01); C07D 213/75 (2013.01); C07D 233/90 (2013.01); C07D 295/205 (2013.01); C07D 305/08 (2013.01); C07J 63/008 (2013.01);
Abstract
Disclosed herein are novel C17-alkanediyl and alkenediyl derivatives of oleanolic acid, including those of the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds. Methods and intermediates useful for making the compounds, and methods of using the compounds, for example, as antioxidant inflammation modulators, and compositions thereof are also provided.