The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 14, 2017
Filed:
Mar. 25, 2015
Applicant:
Merial, Inc., Duluth, GA (US);
Inventors:
Tammy Kolander, Worthington, MN (US);
Paulraj Lawrence, Worthington, MN (US);
Russell Bey, Arden Hills, MN (US);
Assignee:
MERIAL, INC., Duluth, GA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/102 (2006.01); A61K 45/06 (2006.01); C12N 1/36 (2006.01); C12N 1/38 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/102 (2013.01); A61K 45/06 (2013.01); C12N 1/36 (2013.01); C12N 1/38 (2013.01); A61K 2039/522 (2013.01);
Abstract
This disclosure provides attenuatedstrains, compositions comprising same, and methods of production and use thereof. The attenuated strains may express lower or no levels of various virulence-associated genes, relative to the corresponding pathogenic bacteria Advantageously, the attenuatedstrains may be administered orally, intranasally, intra-tracheally, or subcutaneously.