The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 14, 2017
Filed:
Sep. 26, 2012
Applicant:
Universität Zürich Prorektorat Mnw, Zürich, CH;
Inventors:
Christiane Dresch, Seattle, WA (US);
Bruna de Andrade Pereira, Zürich, CH;
Mathias Ackermann, Basserdorf, CH;
Cornel Fraefel, Trüllikon, CH;
Assignee:
University of Zurich, Zürich, CH;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/17 (2006.01); A61K 48/00 (2006.01); A61K 35/76 (2015.01); A61K 31/10 (2006.01); A61K 35/12 (2015.01); C12N 15/11 (2006.01); A61K 31/711 (2006.01); A61K 38/16 (2006.01); C07K 14/47 (2006.01);
U.S. Cl.
CPC ...
A61K 35/76 (2013.01); A61K 31/10 (2013.01); A61K 35/12 (2013.01); A61K 48/0058 (2013.01); C12N 15/11 (2013.01); C12N 2830/008 (2013.01);
Abstract
The invention relates to transgene expression constructs—particularly self inactivating lentiviral vectors—comprising a dendritic cell specific promoter controlling the expression of autoantigen proteins, namely myelin basic protein, proteolipid protein and myelin oligodendrocyte glycoprotein, for use in the therapy of multiple sclerosis.