The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 14, 2017

Filed:

Aug. 07, 2014
Applicant:

Duke University, Durham, NC (US);

Inventors:

Priya S. Kishnani, Durham, NC (US);

Suhrad G. Banugaria, Durham, NC (US);

Dwight D. Koeberl, Durham, NC (US);

Sean N. Prater, Durham, NC (US);

Assignee:

Duke University, Durham, NC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 55/02 (2006.01); A01N 55/08 (2006.01); A61K 31/535 (2006.01); A61K 31/497 (2006.01); A01N 43/38 (2006.01); A61K 31/69 (2006.01); A61K 31/00 (2006.01); A61K 31/519 (2006.01); C07K 16/28 (2006.01); A61K 38/17 (2006.01); A61K 39/395 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/69 (2013.01); A61K 31/00 (2013.01); A61K 31/519 (2013.01); A61K 38/1722 (2013.01); A61K 39/3955 (2013.01); C07K 16/2887 (2013.01); A61K 2039/505 (2013.01); A61K 2039/545 (2013.01); C07K 2317/24 (2013.01);
Abstract

The present invention relates, in general, to a method of treating patients undergoing enzyme replacement therapy (ERT) or other therapy involving the administration of a proteinaceous therapeutic agent as well gene replacement therapy with non-viral or viral vectors, or other therapeutic modality or modalities, used alone or in combination, which involve the administration of exogenous substances for potential therapeutic benefit, including, but not limited to DNA vaccines, siRNA, splice-site switching oligomers (SSOs) as well as RNA-based nanoparticles (RNPs) and nanovaccines. The invention further relates to compounds and compositions suitable for use in such methods.


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