The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 07, 2017
Filed:
May. 05, 2014
Massachusetts Institute of Technology, Cambridge, MA (US);
Peter T. C. So, Boston, MA (US);
Bevin Engelward, Lexington, MA (US);
Timothy Ragan, Somerville, MA (US);
Karsten Bahlman, Cambridge, MA (US);
Ki-Hean Kim, Belmont, MA (US);
Lily Hsu Laiho, San Luis Obispo, CA (US);
Hayden Huang, Chevy Chase, MD (US);
Massachusetts Institute of Technology, Cambridge, MA (US);
Abstract
In accordance with preferred embodiments of the present invention, a method for imaging tissue, for example, includes the steps of mounting the tissue on a computer controlled stage of a microscope, determining volumetric imaging parameters, directing at least two photons into a region of interest, scanning the region of interest across a portion of the tissue, imaging a plurality of layers of the tissue in a plurality of volumes of the tissue in the region of interest, sectioning the portion of the tissue and imaging a second plurality of layers of the tissue in a second plurality of volumes of the tissue in the region of interest, detecting a fluorescence image of the tissue due to said excitation light; and processing three-dimensional data that is collected to create a three-dimensional image of the region of interest.