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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9587281 B1

PDFFull Text
Date of Patent:
Mar. 07, 2017

Filed:

Feb. 12, 2015

Cereblon isoforms and their use as biomarkers for therapeutic treatment

Applicant:

Celgene Corporation, Summit, NJ (US);

Inventors:

Anjan Thakurta, Basking Ridge, NJ (US);

Anita Gandhi, Bernardsville, NJ (US);

Michelle F. Waldman, Florham Park, NJ (US);

Rajesh Chopra, Summit, NJ (US);

Michael Amatangelo, Newtown, PA (US);

Chad Bjorklund, Summit, NJ (US);

Assignee:

CELGENE CORPORATION, Summit, NJ (US);

Attorney:

Jones Day

Primary Examiner:

Peter J Reddig

Int. Cl.
CPC ...
C12Q 1/68 (2006.01); G01N 33/68 (2006.01); G01N 33/574 (2006.01); A61K 31/454 (2006.01); A61K 31/517 (2006.01); C07K 14/47 (2006.01); A61K 31/5377 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); A61K 31/454 (2013.01); A61K 31/517 (2013.01); A61K 31/5377 (2013.01); C07K 14/47 (2013.01); G01N 33/57496 (2013.01); G01N 33/6872 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/158 (2013.01); G01N 2333/4703 (2013.01); G01N 2800/52 (2013.01);
Abstract

Provided herein are cereblon isoforms and methods of their use as biomarkers for treating a disease, disorder, or condition with a treatment compound, e.g., thalidomide, lenalidomide, pomalidomide, 3-(5-amino-2-methyl-4-oxoquinazolin-3(4H)-yl)-piperidine-2,6-dione, or (S)-3-(4-((4-(morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione.

Find Patent Forward Citations

Thakurta, Anjan. (2017). Cereblon isoforms and their use as biomarkers for therapeutic treatment (U.S. Patent No. 9587281). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9587281

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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