The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 07, 2017
Filed:
Sep. 06, 2013
University of Georgia Research Foundation, Inc., Athens, GA (US);
North Carolina State University, Raleigh, NC (US);
Michael W. W. Adams, Athens, GA (US);
Robert M. Kelly, Cary, NC (US);
Aaron B. Hawkins, Durham, NC (US);
Angeli Lal Menon, Athens, GA (US);
Gina Lynette Pries Lipscomb, Athens, GA (US);
Gerrit Jan Schut, Athen, GA (US);
University of Georgia Research Foundation, Inc., Athens, GA (US);
North Carolina State University, Raleigh, NC (US);
Abstract
Provided herein are genetically engineered microbes that include at least a portion of a carbon fixation pathway, and in one embodiment, use molecular hydrogen to drive carbon dioxide fixation. In one embodiment, the genetically engineered microbe is modified to convert acetyl CoA, molecular hydrogen, and carbon dioxide to 3-hydroxypropionate, 4-hydroxybutyrate, acetyl CoA, or the combination thereof at levels greater than a control microbe. Other products may also be produced. Also provided herein are cell free compositions that convert acetyl CoA, molecular hydrogen, and carbon dioxide to 3-hydroxypropionate, 4-hydroxybutyrate, acetyl CoA, or the combination thereof. Also provided herein are methods of using the genetically engineered microbes and the cell free compositions.