The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 07, 2017

Filed:

Feb. 02, 2004
Applicants:

Hikaru Matsuda, Hyogo, JP;

Yoshiki Sawa, Hyogo, JP;

Satoshi Taketani, Osaka, JP;

Shigeru Miyagawa, Osaka, JP;

Inventors:

Hikaru Matsuda, Hyogo, JP;

Yoshiki Sawa, Hyogo, JP;

Satoshi Taketani, Osaka, JP;

Shigeru Miyagawa, Osaka, JP;

Assignee:

CELLSEED INC., Tokyo, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/00 (2006.01); C12N 5/00 (2006.01); C12N 5/02 (2006.01); C12N 5/071 (2010.01); C12N 5/077 (2010.01); A61L 27/38 (2006.01); A61K 35/34 (2015.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
C12N 5/0658 (2013.01); A61K 35/34 (2013.01); A61L 27/3804 (2013.01); A61L 27/3834 (2013.01); A61L 27/3839 (2013.01); A61L 27/3895 (2013.01); C12N 5/0068 (2013.01); C12N 5/0657 (2013.01); A61K 35/12 (2013.01); A61L 2430/20 (2013.01); C12N 2506/02 (2013.01); C12N 2506/1392 (2013.01); C12N 2513/00 (2013.01); C12N 2523/00 (2013.01); C12N 2533/40 (2013.01); C12N 2539/10 (2013.01);
Abstract

The present invention provides a prosthetic tissue or sheet capable of withstanding implantation operations, which can be used in actual operation and can be produced by culture. The present invention also provides a novel therapy which can substitute for cell therapy. Particularly, the present invention provides a method for producing a prosthetic tissue comprising a cell derived from a part other than myocardium and capable of withstanding implantation operation. The above-described objects of the present invention were partially achieved by finding that by culturing cells under specific culture conditions, the cells are unexpectedly organized into a tissue, and the resultant prosthetic tissue is capable of being detached from culture dishes. The present invention also provides a three-dimensional structure applicable to heart, comprising a cell derived from a part other than the myocardium of an adult.


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