The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 07, 2017
Filed:
Jan. 24, 2013
Applicant:
Brown University, Providence, RI (US);
Inventors:
Jeffrey Morgan, Providence, RI (US);
Peter Chai, Providence, RI (US);
Anthony Napolitano, Providence, RI (US);
Edith Mathiowitz, Providence, RI (US);
Dylan Dean, Providence, RI (US);
Assignee:
Brown University, Providence, RI (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12M 1/12 (2006.01); C12N 5/00 (2006.01); C12M 1/32 (2006.01);
U.S. Cl.
CPC ...
C12M 25/00 (2013.01); C12M 23/12 (2013.01); C12M 25/14 (2013.01); C12N 5/0012 (2013.01); C12N 5/0062 (2013.01); C12N 2533/40 (2013.01); C12N 2533/74 (2013.01);
Abstract
Molds for making cell aggregation devices include upper and lower surfaces. Methods of aggregating cells include depositing cells on in a seeding chamber, incubating the cells and removing aggregated cells. Devices for encapsulating aggregates of cells include biocompatible, bio-sustainable substrates compartments and a coating of a biocompatible, bio-sustainable polymer that completely surrounds the substrate and cell-encapsulating compartments.