The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 07, 2017
Filed:
Nov. 25, 2015
Applicant:
Kyowa Hakko Kirin Co., Ltd, Tokyo, JP;
Inventors:
Assignee:
KYOWA HAKKO KIRIN CO., LTD, Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/13 (2006.01); C12N 15/64 (2006.01); C07K 16/28 (2006.01); C12R 1/91 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2878 (2013.01); C12R 1/91 (2013.01); A61K 2039/505 (2013.01); C07K 2317/21 (2013.01); C07K 2317/52 (2013.01); C07K 2317/565 (2013.01); C07K 2317/72 (2013.01); C07K 2317/73 (2013.01); C07K 2317/75 (2013.01); C07K 2317/94 (2013.01);
Abstract
The present invention can provide a monoclonal antibody which comprises a heavy chain constant region which is IgG2 wherein valine at position 234, glutamine at position 237 and proline at position 331 are at least substituted with alanine, alanine and serine, respectively (numbering is based on the EU index of Kabat et al); has an agonist activity; and binds to human CD40.
Matsushima, Aki. (2017). Dna encoding an anti-cd40 igg2 antibody having amino acid mutations (U.S. Patent No. 9587031). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9587031
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile