The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 07, 2017
Filed:
Oct. 26, 2012
Biogen International Neuroscience Gmbh, Zug, CH;
University of Zürich, Zürich, CH;
Roger Nitsch, Zumikon, CH;
Christoph Hock, Erlenbach, CH;
Maria Grazia Barenco Montrasio, Schindellegi, CH;
Fabio Montrasio, Schindellegi, CH;
Jan Grimm, Duebendorf, CH;
Jean-Luc Baeriswyl, Zurich, CH;
Paul Weinreb, Andover, MA (US);
Janaky Coomaraswamy, Zurich, CH;
Omar Quintero-Monzon, Waltham, MA (US);
Biogen International Neuroscience GmbH, Zug, CH;
University of Zürich, Zürich, CH;
Abstract
Provided are novel TAR DNA-binding proteins of 43 kDa ('TDP-43')-specific binding molecules including polypeptides such as human antibodies, as well as fragments, derivatives and variants thereof. Also provided are methods related to these TDP-43 specific binding molecules. Assays, kits, and solid supports related to TDP-43-specific binding molecules, including polypeptides such as, human antibodies are also disclosed. The TDP-43-specific binding molecule, antibody, immunoglobulin chain(s), as well as binding fragments, derivatives and variants thereof can be used in pharmaceutical and diagnostic compositions for TDP-43 targeted immunotherapy and diagnosis, respectively.