The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 07, 2017
Filed:
Mar. 14, 2014
Applicant:
Oncodesign S.a., Dijon, FR;
Inventors:
Petra Marcella Francoise Blom, Destelbergen, BE;
Jan Marie Cyriel Jozef Hoflack, Westmalle, BE;
Pascal Andre Rene Benderitter, Apollinaire, FR;
Assignee:
ONCODESIGN S.A., Dijon, FR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 498/16 (2006.01); A61K 31/519 (2006.01); A61K 31/5025 (2006.01); C07D 487/18 (2006.01); C07D 487/22 (2006.01); C07D 498/18 (2006.01); C07D 498/22 (2006.01); C07D 513/18 (2006.01); C07D 515/18 (2006.01); C07D 491/18 (2006.01); C07D 513/16 (2006.01);
U.S. Cl.
CPC ...
C07D 498/16 (2013.01); A61K 31/5025 (2013.01); A61K 31/519 (2013.01); C07D 487/18 (2013.01); C07D 487/22 (2013.01); C07D 491/18 (2013.01); C07D 498/18 (2013.01); C07D 498/22 (2013.01); C07D 513/16 (2013.01); C07D 513/18 (2013.01); C07D 515/18 (2013.01);
Abstract
The present invention relates to macrocyclic compounds and compositions containing said compounds acting as kinase inhibitors, in particular as inhibitors of SIK kinase, more in particular SIK1, SIK2 and/or SIK3 and/or mutants thereof, for use in the diagnosis, prevention and/or treatment of SIK-kinase associated diseases. Moreover, the present invention provides methods of using said compounds, for instance as a medicine or diagnostic agent.