The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 07, 2017
Filed:
Nov. 06, 2014
Ono Pharmaceutical Co., Ltd., Osaka, JP;
Takayuki Inukai, Osaka, JP;
Jun Takeuchi, Osaka, JP;
Tomoko Yasuhiro, Osaka, JP;
Mark Allan Wolf, Williamsville, NY (US);
Vijay Dattaram Pawar, Choa Chu Kang, SG;
Anjan Chakrabarti, Dover, SG;
Santhosh Kumar Chittimalla, Clementi, SG;
ONO PHARMACEUTICAL CO., LTD., Osaka, JP;
Abstract
A compound represented by the general formula (1) has a pyridone ring structure introduced into a pyrrolo pyrimidine skeleton, so that the compound has a strong Axl inhibitory activity. Consequently, the compound can be used as a therapeutic agent for Axl-related diseases including cancers such as acute myeloid leukemia, melanoma, breast cancer, pancreatic cancer, and glioma, kidney diseases, immune system diseases, and circulatory system diseases.