The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 07, 2017

Filed:

Sep. 28, 2012
Applicants:

Pil Su Ho, Gyeonggi-do, KR;

Dong OH Yoon, Gyeonggi-do, KR;

Sun Young Han, Gyeonggi-do, KR;

Won IL Lee, Gyeonggi-do, KR;

Jung Sook Kim, Gyeonggi-do, KR;

Woul Seong Park, Gyeonggi-do, KR;

Sung OH Ahn, Gyeonggi-do, KR;

Hye Jung Kim, Gyeonggi-do, KR;

Inventors:

Pil Su Ho, Gyeonggi-do, KR;

Dong Oh Yoon, Gyeonggi-do, KR;

Sun Young Han, Gyeonggi-do, KR;

Won Il Lee, Gyeonggi-do, KR;

Jung Sook Kim, Gyeonggi-do, KR;

Woul Seong Park, Gyeonggi-do, KR;

Sung Oh Ahn, Gyeonggi-do, KR;

Hye Jung Kim, Gyeonggi-do, KR;

Assignee:

C&C RESEARCH LABORATORIES, Gyeonggi-Do, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4353 (2006.01); A61K 31/4985 (2006.01); A61K 31/519 (2006.01); C07D 471/14 (2006.01); C07D 487/14 (2006.01); C07D 491/147 (2006.01); C07D 498/14 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 471/14 (2013.01); C07D 487/14 (2013.01); C07D 498/14 (2013.01); C07D 519/00 (2013.01);
Abstract

The present invention relates to novel heterocyclic compounds of formula 1 useful in preparing drugs for treatment of diseases associated with various functions of the histamine 4 receptor. Especially, the said drugs are useful for treatment of inflammatory diseases, allergy, pain, nasal polyps, rhinitis, chronic sinusitis, nasal congestion, nasal itch, asthma, chronic obstructive pulmonary disease, rheumatoid arthritis, atopic dermatitis, psoriasis, eczema, pruritus, itchy skin, urticaria, idiopathic chronic urticaria, scleroderma, conjunctivitis, keratoconjunctivitis, ocular inflammation, dry eye, cardiac dysfunction, arrhythmia, atherosclerosis, multiple sclerosis, inflammatory bowel disease (including colitis, Crohn's disease, ulcerative colitis), inflammatory pain, neuropathic pain, osteoarthritic pain, autoimmune thyroid disease, immune-mediated (also known as type I) diabetes, lupus, post-operative adhesions, vestibular disorders and cancer.


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