The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 07, 2017
Filed:
Jul. 16, 2015
Applicant:
Kadmon Corporation, Llc, New York, NY (US);
Inventors:
Samuel Waksal, New York, NY (US);
Lillian Chiang, Princeton, NJ (US);
Assignee:
KADMON CORORATION, LLC, New York, NY (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/517 (2006.01); C07D 239/94 (2006.01); C07D 403/12 (2006.01); A61K 39/395 (2006.01); C07K 16/32 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07D 403/12 (2013.01); A61K 31/517 (2013.01); A61K 39/3955 (2013.01); A61K 39/39558 (2013.01); C07K 16/32 (2013.01); A61K 2039/505 (2013.01); A61K 2039/55511 (2013.01);
Abstract
The present invention provides a method of treating breast cancer that is nonresponsive to treatment with trastuzumab, comprising administering to a subject in need of such treatment a therapeutically effective amount of compound N-(3,4-dichloro-2-fluorophenyl)-7-({[(3aR,6aS)-2-methyloctahydrocyclopenta[c]pyrrol-5-yl]methyl}oxy)-6-(methyloxy)quinazolin-4-amine, or a pharmaceutically acceptable salt thereof.