The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 07, 2017

Filed:

Jul. 28, 2011
Applicants:

Bayard R. Huck, Sudbury, MA (US);

Xiaoling Chen, Chestnut Hill, MA (US);

Constantin Neagu, Belmont, MA (US);

Reinaldo Jones, Lowell, MA (US);

Yufang Xiao, Lexington, MA (US);

Igor Mochalkin, San Diego, CA (US);

Inventors:

Bayard R. Huck, Sudbury, MA (US);

Xiaoling Chen, Chestnut Hill, MA (US);

Constantin Neagu, Belmont, MA (US);

Reinaldo Jones, Lowell, MA (US);

Yufang Xiao, Lexington, MA (US);

Igor Mochalkin, San Diego, CA (US);

Assignee:

Merck Patent GmbH, Darmstadt, DE;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/54 (2006.01); C07D 239/42 (2006.01); C07D 401/04 (2006.01); A01N 43/42 (2006.01); A61K 31/47 (2006.01); C07D 403/12 (2006.01); C07D 233/90 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 403/10 (2006.01); C07D 405/12 (2006.01); C07D 405/14 (2006.01); A61K 31/4709 (2006.01); A61K 31/517 (2006.01); A61K 45/06 (2006.01); C07D 403/14 (2006.01);
U.S. Cl.
CPC ...
C07D 403/12 (2013.01); A61K 31/4709 (2013.01); A61K 31/517 (2013.01); A61K 45/06 (2013.01); C07D 233/90 (2013.01); C07D 401/04 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/10 (2013.01); C07D 403/14 (2013.01); C07D 405/12 (2013.01); C07D 405/14 (2013.01);
Abstract

The invention provides novel cyclic amine azaheterocyclic carboxamide according to Formula (I), Formula (II) and Formula (III) their manufacture and use for the treatment of hyperproliferative diseases, such as cancer.


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