The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 07, 2017

Filed:

Jun. 20, 2016
Applicant:

General Electric Company, Schenectady, NY (US);

Inventors:

Matthew David Butts, Rexford, NY (US);

Robert Edgar Colborn, Niskayuna, NY (US);

Peter John Bonitatibus, Jr., Saratoga Springs, NY (US);

Andrew Soliz Torres, Troy, NY (US);

Assignee:

General Electric Company, Niskayuna, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 49/04 (2006.01); A61K 49/10 (2006.01); A61K 49/18 (2006.01); B82Y 5/00 (2011.01);
U.S. Cl.
CPC ...
A61K 49/101 (2013.01); A61K 49/1818 (2013.01); B82Y 5/00 (2013.01); A61K 49/04 (2013.01); A61K 49/0485 (2013.01); Y10S 977/773 (2013.01); Y10S 977/927 (2013.01); Y10S 977/928 (2013.01);
Abstract

Compositions of nanoparticles functionalized with at least one zwitterionic moiety, methods for making a plurality of nanoparticles, and methods of their use as diagnostic agents are provided. The nanoparticles have characteristics that result in minimal retention of the particles in the body compared to other nanoparticles. The nanoparticle comprising a nanoparticulate transition metal oxide covalently functionalized with a silane-functionalized non-targeting zwitterionic moiety.


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