The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 07, 2017

Filed:

Dec. 06, 2013
Applicant:

Kissei Pharmaceutical Co., Ltd., Matsumoto-shi, Nagano, JP;

Inventors:

Toshihiro Nishimura, Azumino, JP;

Yasunori Ueno, Azumino, JP;

Kiyoshi Kasai, Azumino, JP;

Masako Yoshida, Azumino, JP;

Assignee:

KISSEI PHARMACEUTICAL CO., LTD., Matsumoto-shi, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); C07D 487/14 (2006.01); C07D 471/04 (2006.01); A61K 45/06 (2006.01); A61K 31/55 (2006.01); C12N 15/09 (2006.01); A61K 31/13 (2006.01); A61K 31/198 (2006.01); A61K 31/423 (2006.01);
U.S. Cl.
CPC ...
A61K 31/519 (2013.01); A61K 31/13 (2013.01); A61K 31/198 (2013.01); A61K 31/423 (2013.01); A61K 31/55 (2013.01); A61K 45/06 (2013.01); C07D 471/04 (2013.01); C12N 15/09 (2013.01);
Abstract

[Problem] To provide a novel compound that exhibits an agonistic effect on dopamine Dreceptors. [Solution] The present invention provides a compound represented by the general formula (I): in which Ris Calkyl or the like; Ris hydrogen or the like; Rand Rare each hydrogen, Calkyl, RRN—Calkyl, aralkyl, or the like; Rand Rare hydrogen or the like; and Ris hydrogen or the like, or a pharmaceutically acceptable salt thereof, a pharmaceutical compositions containing same and uses for said compound/salt and composition. The compounds of the present invention exhibit potent dopamine Dreceptor simulating activities and thus are useful as a treating or preventing agent for Parkinson's disease and the like.


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