The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 07, 2017
Filed:
Oct. 22, 2015
Applicant:
Consejo Superior DE Investigaciones Cientificas (Csic), Madrid, ES;
Inventors:
Ana Martinez Gil, Madrid, ES;
Carmen Gil Ayuso-Gontan, Madrid, ES;
Valle Palomo Ruiz, Madrid, ES;
Concepcion Perez Martin, Madrid, ES;
Daniel I. Perez Fernandez, Madrid, ES;
Julio Alberto Reyes Rodriguez, Madrid, ES;
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4704 (2006.01); A61K 45/06 (2006.01); C07D 215/56 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4704 (2013.01); A61K 45/06 (2013.01); C07D 215/56 (2013.01);
Abstract
The present invention relates to heterocyclic substituted quinoline derivatives as allosteric inhibitors of the glycogen synthase kinase-3 (GSK-3) enzyme. Therefore, these compounds are useful for the manufacturing of a medicament designed for the treatment and/or prevention of diseases wherein GSK-3 is involved, such as neurodegenerative diseases, inflammatory diseases, cancer, diabetes, and to promote various regenerative processes.