The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 07, 2017
Filed:
Jul. 30, 2012
Masahiro Yoshida, Pittsburgh, PA (US);
C. Douglas Bernstein, Pittsburgh, PA (US);
Onur Dur, San Ramon, CA (US);
Kerem Pekkan, Pittsburgh, PA (US);
Masahiro Yoshida, Pittsburgh, PA (US);
C. Douglas Bernstein, Pittsburgh, PA (US);
Onur Dur, San Ramon, CA (US);
Kerem Pekkan, Pittsburgh, PA (US);
Carnegie Mellon University, Pittsburgh, PA (US);
University of Pittsburgh-Of the Commonwealth System of Higher Education, Pittsburgh, PA (US);
Abstract
Artificial heart valve structures and methods of their fabrication are disclosed. The heart valve structures may be fabricated from a biocompatible polymer and include one or more heart valve leaflet structures incorporated within a conduit. The valve structures may incorporate one or more conduit sinuses, as well as a gap between the lower margin of the valve leaflets and the interior of the conduit. In addition, the valve structures may include one or more valve sinuses created in a space between the valve leaflets and the conduit inner surface. Computational fluid dynamics and mechanical modeling may be used to design the valve leaflets with optimal characteristics. A heart valve structure may also incorporate a biodegradable component to which cells may adhere The incorporated cells may arise from patient cells migrating to the biodegradable component, or the component may be pre-seeded with cells prior to implantation in a patient.