The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 28, 2017

Filed:

May. 18, 2011
Applicants:

Mario Cindric, Zagreb, HR;

Zdenko Hamersak, Zagreb, HR;

Ivana Dodig, Zagreb, HR;

Inventors:

Mario Cindric, Zagreb, HR;

Zdenko Hamersak, Zagreb, HR;

Ivana Dodig, Zagreb, HR;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); C07C 303/02 (2006.01); C07C 303/22 (2006.01); C07C 333/04 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6848 (2013.01); C07C 303/02 (2013.01); C07C 303/22 (2013.01); C07C 333/04 (2013.01);
Abstract

Present invention refers to a novel and improved method of derivatization and detection of amino acid sequence and/or identification of proteins, peptides by a new derivatization compound. Precisely, the method discloses a novel approach to derivatization of peptides or proteins by compounds comprising two or more sulfonyl groups and analysis of derivatized analytes in negative mode of operation of mass spectrometer. This method allows unambiguous analysis of amino acid sequence of long-chain peptides/proteins. Also, the invention discloses a novel synthesis procedure of 5-formyl-benzene-1,3-disulphonic acid as derivatization compound.


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