The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 28, 2017

Filed:

May. 29, 2014
Applicant:

Pacific Biosciences of California, Inc., Menlo Park, CA (US);

Inventors:

Aaron Rulison, Los Altos, CA (US);

Mark McDonald, Milpitas, CA (US);

Paul Lundquist, San Francisco, CA (US);

Assignee:

Pacific Biosciences of California, Menlo Park, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 21/75 (2006.01); G02B 3/00 (2006.01); G01N 21/64 (2006.01); G01J 3/28 (2006.01); G01J 3/36 (2006.01); G02B 13/00 (2006.01);
U.S. Cl.
CPC ...
G01N 21/75 (2013.01); G01J 3/2803 (2013.01); G01J 3/36 (2013.01); G01N 21/6452 (2013.01); G02B 3/0056 (2013.01); G02B 3/0062 (2013.01); G02B 13/006 (2013.01); G02B 13/0065 (2013.01); G02B 13/0085 (2013.01); G01N 21/6428 (2013.01);
Abstract

Apparatus, systems and methods for use in analyzing discrete reactions are provided. The analytical devices of the invention use an array of nanoscale regions (a chip) that has discrete patches of nanoscale regions. The chip mates with a collection device comprising an array of compact lens trains (CLTs) where each of the CLTs corresponds to a single patch of nanoscale regions. Each CLT collects the emitted light from a patch on the chip, collimates the light, performs color separation on the collimated emitted light, and focuses the separated light onto a portion of pixels on the detector below the CLT. Such systems are useful for monitoring many analytical reactions at one time including single molecule sequencing reactions.


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