The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 28, 2017

Filed:

Dec. 24, 2009
Applicants:

Jerome I. Rotter, Los Angeles, CA (US);

Kent D. Taylor, Ventura, CA (US);

Stephan R. Targan, Santa Monica, CA (US);

Talin Haritunians, Encino, CA (US);

Dermot P. Mcgovern, Los Angeles, CA (US);

Xiuqing Guo, Santa Monica, CA (US);

Inventors:

Jerome I. Rotter, Los Angeles, CA (US);

Kent D. Taylor, Ventura, CA (US);

Stephan R. Targan, Santa Monica, CA (US);

Talin Haritunians, Encino, CA (US);

Dermot P. McGovern, Los Angeles, CA (US);

Xiuqing Guo, Santa Monica, CA (US);

Assignee:

CEDARS-SINAI MEDICAL CENTER, Los Angeles, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6883 (2013.01); C12Q 2600/118 (2013.01); C12Q 2600/156 (2013.01); G01N 2800/067 (2013.01);
Abstract

Disclosed are methods of predicting the development of medically refractory ulcerative colitis (MR-UC) in a patient In one embodiment, disclosed is a method of prognosing ulcerative colitis in an individual by determining the presence or absence of one or more risk variants, where the presence of one or more risk variants is indicative of a severe and/or aggressive form of ulcerative colitis. In another embodiment, the severe form of ulcerative colitis is indicative of MR-UC.


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