The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 28, 2017

Filed:

Aug. 15, 2013
Applicants:

Biotium, Inc., Hayward, CA (US);

Allelogic Biosciences Corporation, Hayward, CA (US);

Inventors:

Fei Mao, Fremont, CA (US);

Wai-Yee Leung, San Ramon, CA (US);

Xing Xin, Foster City, CA (US);

Assignee:

Biotium, Inc., Hayward, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 19/04 (2006.01); C12Q 1/68 (2006.01); C07H 21/00 (2006.01); C07D 209/08 (2006.01); C07D 213/38 (2006.01); C07D 221/10 (2006.01); C07D 417/06 (2006.01); C07D 417/14 (2006.01); C07D 491/147 (2006.01); C09B 15/00 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6876 (2013.01); C07D 209/08 (2013.01); C07D 213/38 (2013.01); C07D 221/10 (2013.01); C07D 417/06 (2013.01); C07D 417/14 (2013.01); C07D 491/147 (2013.01); C07H 21/00 (2013.01); C09B 15/00 (2013.01); C12Q 1/686 (2013.01); C12Q 1/6851 (2013.01);
Abstract

Dimeric and trimeric nucleic acid dyes, and associated systems and methods are provided. Such a dye may form a hairpin-like structure that enables it to stain nucleic acids via a release-on-demand mechanism, for example. Such a dye may have low background fluorescence in the absence of nucleic acids and high fluorescence in the presence of nucleic acids, upon binding therewith, for example. A dye provided herein may be useful in a variety of applications, such as in DNA quantitation in real-time PCR, for example.


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