The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 28, 2017
Filed:
Dec. 23, 2013
Applicant:
Invista North America S.á R.l., Wilmington, DE (US);
Inventors:
Adriana Leonora Botes, Rosedale East, GB;
Alex Van Eck Conradie, Eaglescliffe, GB;
Changlin Chen, Ingleby Barwick, GB;
Paul S. Pearlman, Thornton, PA (US);
Assignee:
INVISTA NORTH AMERICA S.A.R.L., Wilmington, DE (US);
Primary Examiner:
Int. Cl.
CPC ...
C12P 13/00 (2006.01); C12P 7/18 (2006.01); C12P 7/42 (2006.01); C12P 7/44 (2006.01); C12N 15/52 (2006.01);
U.S. Cl.
CPC ...
C12P 13/001 (2013.01); C12N 15/52 (2013.01); C12P 7/18 (2013.01); C12P 7/42 (2013.01); C12P 7/44 (2013.01); C12P 13/005 (2013.01);
Abstract
This document describes biochemical pathways for producing pimelic acid, 7-aminoheptanoic acid, 7-hydroxyheptanoic acid, heptamethylenediamine or 1,7-heptanediol by forming one or two terminal functional groups, each comprised of carboxyl, amine or hydroxyl group, in a C7 aliphatic backbone substrate. These pathways, metabolic engineering and cultivation strategies described herein rely on the C1 elongation enzymes or homolog associated with coenzyme B biosynthesis.