The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 28, 2017
Filed:
Dec. 17, 2014
Applicant:
The Scripps Research Institute, La Jolla, CA (US);
Inventors:
Jason W. Chin, Cambridge, GB;
T. Ashton Cropp, Bethesda, MD (US);
J. Christopher Anderson, San Francisco, CA (US);
Peter G. Schultz, La Jolla, CA (US);
Assignee:
The Scripps Reserach Institute, La Jolla, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/81 (2006.01); A61K 38/17 (2006.01); C12N 9/00 (2006.01); C12N 15/67 (2006.01);
U.S. Cl.
CPC ...
C12N 15/81 (2013.01); A61K 38/1709 (2013.01); C12N 9/93 (2013.01); C12N 15/67 (2013.01); C12Y 601/01 (2013.01); C12Y 601/01001 (2013.01); C12Y 601/0102 (2013.01); Y10S 435/81 (2013.01); Y10S 435/975 (2013.01);
Abstract
This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided.