The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 28, 2017

Filed:

Sep. 22, 2014
Applicant:

Eberhard-karls-universitaet Tuebingen Universitaetsklinikum, Tuebingen, DE;

Inventors:

Hans-Jorg Buhring, Tubingen, DE;

Sabrina Grimm, Rottenburg a.N., DE;

Flavianna Cerabona, Bissingen, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C12N 5/00 (2006.01); C12N 5/0775 (2010.01); C07K 16/28 (2006.01); C07K 16/40 (2006.01); G01N 33/569 (2006.01); A61K 35/28 (2015.01); A61K 39/00 (2006.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
C12N 5/0663 (2013.01); A61K 35/28 (2013.01); C07K 16/28 (2013.01); C07K 16/2803 (2013.01); C07K 16/2863 (2013.01); C07K 16/40 (2013.01); G01N 33/56966 (2013.01); A61K 2035/124 (2013.01); A61K 2039/507 (2013.01); G01N 2333/705 (2013.01); G01N 2333/70503 (2013.01); G01N 2333/71 (2013.01); G01N 2333/916 (2013.01);
Abstract

The present invention relates to the use of at least one antibody which binds to the SUSD2 antigen, or to functional fragments of the antibody, in combination with at least one of the following: an antibody which binds to CD140b, an antibody which binds to CD56, and/or an antibody which binds to TNAP, or functional fragments thereof, for isolation of mesenchymal stem cells, especially those having particularly chondrocytic and osteogenic differentiation potential. The invention further relates to processes for isolating such stem cells using these antibodies.


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