The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 28, 2017
Filed:
May. 12, 2015
Applicant:
Eli Lilly and Company, Indianapolis, IN (US);
Inventors:
Donmienne Doen Mun Leung, San Diego, CA (US);
Ling Liu, Carmel, IN (US);
Jirong Lu, Carmel, IN (US);
Ying Tang, San Diego, CA (US);
Jianghuai Xu, San Diego, CA (US);
Assignee:
Eli Lilly and Company, Indianapolis, IN (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); C07K 16/00 (2006.01); C07K 16/22 (2006.01); C07K 16/40 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
C07K 16/22 (2013.01); C07K 16/2863 (2013.01); C07K 16/40 (2013.01); A61K 2039/505 (2013.01); C07K 2317/14 (2013.01); C07K 2317/31 (2013.01); C07K 2317/33 (2013.01); C07K 2317/56 (2013.01); C07K 2317/622 (2013.01); C07K 2317/64 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01); C07K 2319/00 (2013.01);
Abstract
The present invention relates to compounds that bind to human vascular endothelial growth factor receptor-2 (VEGFR2) and human angiopoietin-2 (Ang2), and may be useful for treating cancer, especially solid tumors driven by VEGFR2 and Ang2, including gastric, hepatocellular carcinoma, ovarian, colorectal, non-small cell lung, biliary tract, and breast cancers.