The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 28, 2017
Filed:
Feb. 07, 2013
Hanall Biopharma Co., Ltd., Daegu, KR;
Sung Wuk Kim, Gyeonggi-do, KR;
Seung Kook Park, Seoul, KR;
Yeon Jung Song, Gyeonggi-do, KR;
Eun Sun Kim, Seoul, KR;
Hyea Kyung Ahn, Gyeonggi-do, KR;
Jae Kap Jeong, Gyeonggi-do, KR;
Hung Keun Lee, Seoul, KR;
HANALL BIOPHARMA CO., LTD., Daegu, KR;
Abstract
The present invention relates to new uses of modified human tumor necrosis factor receptor-1 (TNFRI) polypeptide, and more particularly, to uses thereof for prevention and treatment of dry eye syndrome. The modified TNFRI or modified TNFRI fragment of the present invention has excellent TNFα neutralizing activity, and inhibits TNFα activity on the ocular surface of the patient to suppress inflammation induction effects related to dry eye. Therefore, the modified TNFRI or modified TNFRI fragment of the present invention exhibits remarkable effects in the prevention and treatment of dry eye syndrome, and thus can be very useful in the prevention and treatment of dry eye syndrome.