The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 28, 2017
Filed:
Feb. 19, 2016
Council of Scientific and Industrial Research, New Delhi, IN;
Kotamraju Srigiridhar, Hyderabad, IN;
Karnewar Santosh, Hyderabad, IN;
Vasamsetti Sathish Babu, Hyderabad, IN;
Togapur Pavan Kumar, Hyderabad, IN;
Basi Venkata Subba Reddy, Hyderabad, IN;
Jerald Mahesh Kumar, Hyderabad, IN;
Council of Scientific and Industrial Research, New Delhi, IN;
Abstract
The present invention relates to an antioxidant compound having anti atherosclerotic effect and preparation thereof. The present invention more particularly relates to the synthesis of TPP+ coupled esculetin (mitochondria-targeted esculetin [Mito-Esc]) followed by the biological evaluation of Mito-Esc for its ability to attenuate Angiotensin-II-induced atherosclerosis in apolipoproteinE knockout (ApoEmice along with the endothelial cell age-delaying effects of Mito-Esc.