The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 28, 2017
Filed:
May. 04, 2012
Finite fully addressable nucleic acid nanostructures as nanocarriers for delivery of pharmaceuticals
Chris Dwyer, Durham, NC (US);
Hong Zhong, Huntington, WV (US);
Michael Norton, Huntington, WV (US);
Steven Armentrout, Reston, VA (US);
Chris Dwyer, Durham, NC (US);
Hong Zhong, Huntington, WV (US);
Michael Norton, Huntington, WV (US);
Steven Armentrout, Reston, VA (US);
PARABON NANOLABS, INC., Reston, VA (US);
Abstract
The present invention provides nanostructures that are particularly well suited for delivery of bioactive agents to organs, tissues, and cells of interest in vivo, and for diagnostic purposes. In exemplary embodiments, the nanostructures are complexes of DNA strands having fully defined nucleotide sequences that hybridize to each other in such a way as to provide a pre-designed three dimensional structure with binding sites for targeting molecules and bioactive agents. The nanostructures are of a pre-designed finite length and have a pre-defined three dimensional structure.