IDiyas

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9579380 B1

PDFFull Text
Date of Patent:
Feb. 28, 2017

Filed:

Mar. 16, 2005

Microporation of tissue for delivery of bioactive agents

Applicant:

Jonathan A. Eppstein, Atlanta, GA (US);

Inventor:

Jonathan A. Eppstein, Atlanta, GA (US);

Assignee:

NTT DENKO CORPORATION, Tokyo, JP;

Attorney:

King & Spalding LLP

Primary Examiner:

Edelmira Bosques

Int. Cl.
CPC ...
A61N 1/30 (2006.01); A61K 41/00 (2006.01); A61B 1/313 (2006.01); A61B 5/145 (2006.01); A61B 18/04 (2006.01); A61M 37/00 (2006.01); A61N 1/32 (2006.01); A61B 5/15 (2006.01); A61B 5/151 (2006.01); A61B 18/10 (2006.01); A61B 18/20 (2006.01); A61B 17/00 (2006.01); A61B 18/00 (2006.01); A61N 1/04 (2006.01); A61N 7/00 (2006.01);
U.S. Cl.
CPC ...
A61K 41/0047 (2013.01); A61B 1/313 (2013.01); A61B 5/14514 (2013.01); A61B 5/150022 (2013.01); A61B 5/150076 (2013.01); A61B 5/150083 (2013.01); A61B 5/150091 (2013.01); A61B 5/150099 (2013.01); A61B 5/150129 (2013.01); A61B 5/15136 (2013.01); A61B 5/150175 (2013.01); A61B 18/04 (2013.01); A61M 37/0092 (2013.01); A61N 1/325 (2013.01); A61N 1/327 (2013.01); A61B 18/10 (2013.01); A61B 18/203 (2013.01); A61B 2017/00026 (2013.01); A61B 2017/00172 (2013.01); A61B 2017/00765 (2013.01); A61B 2018/00452 (2013.01); A61B 2018/00577 (2013.01); A61B 2018/00642 (2013.01); A61B 2018/00791 (2013.01); A61M 2037/0007 (2013.01); A61N 1/0412 (2013.01); A61N 1/0428 (2013.01); A61N 1/0476 (2013.01); A61N 2007/0034 (2013.01);
Abstract

A method of enhancing the permeability of a biological membrane, including the skin or mucosa of an animal or the outer layer of a plant to a permeant is described utilizing microporation of selected depth and optionally one or more of sonic, electromagnetic, mechanical and thermal energy and a chemical enhancer. Microporation is accomplished to form a micropore of selected depth in the biological membrane and the porated site is contacted with the permeant. Additional permeation enhancement measures may be applied to the site to enhance both the flux rate of the permeant into the organism through the micropores as well as into targeted tissues within the organism.

Find Patent Forward Citations

Loading…