The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 28, 2017
Filed:
Feb. 20, 2009
Applicants:
Mariagrazia Pizza, Siena, IT;
Maria Scarselli, Siena, IT;
Marzia Monica Giuliani, Siena, IT;
Maria Arico, Poggibonsi, IT;
Rino Rappuoli, Castelnuovo Berardenga, IT;
Inventors:
Mariagrazia Pizza, Siena, IT;
Maria Scarselli, Siena, IT;
Marzia Monica Giuliani, Siena, IT;
Maria Arico, Poggibonsi, IT;
Rino Rappuoli, Castelnuovo Berardenga, IT;
Assignee:
GlaxoSmithKline Biologicals SA, Rixensart, BE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/095 (2006.01); A61K 39/02 (2006.01); A61K 39/38 (2006.01); A61K 38/00 (2006.01); C07K 1/00 (2006.01); C07H 21/04 (2006.01); C12N 15/00 (2006.01); C07K 14/22 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/095 (2013.01); C07K 14/22 (2013.01); A61K 39/00 (2013.01);
Abstract
fHBP is a protein in. Three families of fHBP are known. To increase the ability of a fHBP protein to elicit antibodies that are cross-reactive between the families, fHBP is selected or engineered to have a sequence which can elicit broad-spectrum bactericidal anti-meningococcal antibodies after administration to a host animal.