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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9579361 B1

PDFFull Text
Date of Patent:
Feb. 28, 2017

Filed:

Sep. 01, 2015

Wnt antagonist and methods of treatment and screening

Applicant:

Oncomed Pharmaceuticals, Inc., Redwood City, CA (US);

Inventors:

Sanjeev H. Satyal, San Carlos, CA (US);

Satyajit Sujit Kumar Mitra, South Pasadena, CA (US);

Austin L. Gurney, San Francisco, CA (US);

Assignee:

ONCOMED PHARMACEUTICALS, INC., Redwood City, CA (US);

Attorney:

Sterne, Kessler, Goldstein and Fox P.L.L.C.

Primary Examiner:

Alana Harris Dent

Int. Cl.
CPC ...
A61K 6/00 (2006.01); A61K 31/00 (2006.01); A61K 31/28 (2006.01); A61K 31/282 (2006.01); A61K 31/33 (2006.01); A61K 31/335 (2006.01); A61K 31/337 (2006.01); A61K 39/00 (2006.01); A61K 39/395 (2006.01); A61K 45/00 (2006.01); A61K 38/17 (2006.01); C07K 14/705 (2006.01); G01N 33/50 (2006.01); A61K 31/4745 (2006.01); A61K 31/7068 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/177 (2013.01); A61K 31/282 (2013.01); A61K 31/337 (2013.01); A61K 31/4745 (2013.01); A61K 31/7068 (2013.01); A61K 39/39591 (2013.01); C07K 14/705 (2013.01); G01N 33/5011 (2013.01); A61K 38/00 (2013.01); C07K 2319/02 (2013.01); C07K 2319/30 (2013.01); C07K 2319/70 (2013.01);
Abstract

The present invention relates to compositions comprising Wnt antagonists and methods of treating Wnt-associated diseases and disorders, such as cancer, inducing differentiation, and reducing the frequency of cancer stem cells, as well as novel methods of screening for such Wnt antagonists. In particular, the invention discloses soluble FZD, SFRP and Ror receptors and their use.

Find Patent Forward Citations

Satyal, Sanjeev. (2017). Wnt antagonist and methods of treatment and screening (U.S. Patent No. 9579361). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9579361

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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