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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9579346 B1

PDFFull Text
Date of Patent:
Feb. 28, 2017

Filed:

May. 06, 2014

Treatment of macrophage-related disorders

Applicants:

Neuraltus Pharmaceuticals, Inc., Palo Alto, CA (US);

The Regents of the University of California, Oakland, CA (US);

Inventors:

Michael S. McGrath, Burlingame, CA (US);

Arasteh Ari Azhir, Los Altos, CA (US);

Assignees:

The Regents of the Univerity of California, Oakland, CA (US);

Neuraltus Pharmaceuticals, Inc., Palo Alto, CA (US);

Attorney:

Wilson Sonsini Goodrich & Rosati

Primary Examiner:

Johann R Richter

Assistant Examiner:

Robert Cabral

Int. Cl.
CPC ...
A61K 33/20 (2006.01); A61K 31/10 (2006.01); A61K 31/185 (2006.01); A61K 31/327 (2006.01); A61K 33/00 (2006.01); A61K 33/04 (2006.01); A61K 33/16 (2006.01); A61K 33/18 (2006.01); A61K 33/24 (2006.01); A61K 33/32 (2006.01); A61K 33/38 (2006.01); A61K 33/40 (2006.01); A61K 45/06 (2006.01); A61K 31/137 (2006.01); A61K 31/7076 (2006.01); A61K 39/395 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
A61K 33/20 (2013.01); A61K 31/10 (2013.01); A61K 31/137 (2013.01); A61K 31/185 (2013.01); A61K 31/327 (2013.01); A61K 31/7076 (2013.01); A61K 33/00 (2013.01); A61K 33/04 (2013.01); A61K 33/16 (2013.01); A61K 33/18 (2013.01); A61K 33/24 (2013.01); A61K 33/32 (2013.01); A61K 33/38 (2013.01); A61K 33/40 (2013.01); A61K 39/3955 (2013.01); A61K 45/06 (2013.01); C07K 16/2839 (2013.01); G01N 2333/70596 (2013.01);
Abstract

The present invention provides a method of treating a macrophage related disease comprising administering to a subject in need thereof an effective amount of an oxidative agent or an immunosuppressive agent. The present invention also provides a method of modulating macrophage accumulation or activation comprising administering to a subject in need thereof an effective amount of an oxidative agent or an immunosuppressive agent. The oxidative agent can be chlorite or a chlorite containing compound.

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