The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 28, 2017
Filed:
May. 28, 2014
Applicant:
Redx Pharma Plc, Cheshire, GB;
Inventors:
Richard Armer, Liverpool, GB;
Matilda Bingham, Liverpool, GB;
Inder Bhamra, Liverpool, GB;
Andrew McCarroll, Liverpool, GB;
Assignee:
Redx Pharma PLC, Manchester, GB;
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/502 (2006.01); C07D 237/30 (2006.01); C07D 401/14 (2006.01); C07D 471/04 (2006.01); A61K 31/501 (2006.01); A61K 31/5025 (2006.01); A61K 31/506 (2006.01); A61K 31/5377 (2006.01); C07D 417/14 (2006.01);
U.S. Cl.
CPC ...
A61K 31/502 (2013.01); A61K 31/501 (2013.01); A61K 31/506 (2013.01); A61K 31/5025 (2013.01); A61K 31/5377 (2013.01); C07D 237/30 (2013.01); C07D 401/14 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01);
Abstract
This invention relates to novel compounds of formula (I). The compounds of the invention are hedgehog pathway antagonists. Specifically, the compounds of the invention are useful as Smoothened (SMO) inhibitors. The invention also contemplates the use of the compounds for treating conditions treatable by the inhibition of the Hedgehog pathway and SMO, for example cancer.