The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 21, 2017

Filed:

Mar. 11, 2015
Applicant:

Advanced Liquid Logic, Inc., San Diego, CA (US);

Inventors:

Allen E Eckhardt, San Diego, CA (US);

Carrie Graham, Raleigh, NC (US);

Ramakrishna Sista, San Diego, CA (US);

Vamsee K. Pamula, Cary, NC (US);

Theodore Winger, Morrisville, NC (US);

Tong Wang, Cary, NC (US);

Yalin Xiong, Morrisville, NC (US);

Ning Wu, Raleigh, NC (US);

Sanjay Saha, Andhra Pradesh, IN;

Gajendrasinh Raolji, Andhra Pradesh, IN;

Raveendra Dayam, Andhra Pradesh, IN;

Assignee:

Advanced Liquid Logic, Inc., San Diego, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/54 (2006.01); C12Q 1/34 (2006.01); C07D 311/18 (2006.01); C07D 311/20 (2006.01); C07H 15/203 (2006.01); C12Q 1/25 (2006.01); G01N 33/543 (2006.01); G01N 21/64 (2006.01); C07D 311/16 (2006.01); C07D 405/12 (2006.01); C07D 413/12 (2006.01); C07H 17/075 (2006.01); C12Q 1/44 (2006.01); B01L 3/00 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/34 (2013.01); C07D 311/16 (2013.01); C07D 311/18 (2013.01); C07D 311/20 (2013.01); C07D 405/12 (2013.01); C07D 413/12 (2013.01); C07H 15/203 (2013.01); C07H 17/075 (2013.01); C12Q 1/25 (2013.01); C12Q 1/44 (2013.01); C12Q 1/54 (2013.01); G01N 21/6452 (2013.01); G01N 33/5438 (2013.01); B01L 3/502784 (2013.01); B01L 2300/0654 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/18 (2013.01); B01L 2400/043 (2013.01); B01L 2400/0427 (2013.01); G01N 2333/916 (2013.01); G01N 2333/926 (2013.01); G01N 2800/04 (2013.01);
Abstract

The invention is directed to droplet actuator devices and assay methods. The invention includes assay methods of conducting an assay comprising combining a sample with an umbelliferyl derivative, wherein the sample potentially comprises an enzyme capable of cleaving the umbelliferyl derivative and where the umbelliferyl derivative comprises an umbelliferyl core modified with one or more modifying moieties.


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