The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 21, 2017

Filed:

Feb. 11, 2015
Applicant:

Stemnion, Inc., Pittsburgh, PA (US);

Inventors:

Howard C Wessel, New Kensington, PA (US);

Richard A Banas, Turtle Creek, PA (US);

Assignee:

STEMNION, INC., Pittsburgh, PA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/0783 (2010.01); C12N 5/073 (2010.01); C12N 5/0789 (2010.01); C12N 5/077 (2010.01); A61K 38/17 (2006.01); A61K 35/12 (2015.01); A61K 38/18 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0636 (2013.01); A61K 35/12 (2013.01); A61K 38/1793 (2013.01); A61K 38/1866 (2013.01); C12N 5/0605 (2013.01); C12N 5/0647 (2013.01); C12N 5/0656 (2013.01); C12N 2501/135 (2013.01); C12N 2501/15 (2013.01); C12N 2501/165 (2013.01); C12N 2501/40 (2013.01); C12N 2501/48 (2013.01); C12N 2501/73 (2013.01); C12N 2502/025 (2013.01);
Abstract

The invention is directed to methods for reducing the number of apoptotic cell deaths in a population of cells undergoing excessive cellular apoptosis. The invention is also directed to methods for preventing apoptotic cell death in a population of cells at risk for developing excessive cellular apoptosis. In particular, the invention is directed to methods for reducing or preventing excessive cellular apoptosis comprising exposing cells exhibiting or at risk for developing excessive cellular apoptosis to a cellular factor-containing composition called Amnion-derived Cellular Cytokine Solution (referred to herein as ACCS), which is obtained from the culturing of Amnion-derived Multipotent Progenitor (AMP) cells, or AMP cells.


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