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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9574176 B1

PDFFull Text
Expired
Date of Patent:
Feb. 21, 2017

Filed:

Oct. 29, 2013

Neural stem cell having increased passage ability, method for manufacturing neural stem cell having said increased passage abiility, and method for culturing neural stem cells for increasing passage ability of neural stem cells

Applicant:

Eisai R&d Management Co., Ltd., Tokyo, JP;

Inventors:

Norimasa Miyamoto, Tsukuba, JP;

Yuichi Ono, Kobe, JP;

Kana Namiki, Kobe, JP;

Yoshitoshi Kasuya, Chiba, JP;

Assignee:

Eisai R&D Management Co., Ltd., Tokyo, JP;

Attorney:

Fish & Richardson P.C.

Primary Examiner:

Shin Lin Chen

Int. Cl.
CPC ...
A61K 48/00 (2006.01); C12N 5/00 (2006.01); C12N 5/08 (2006.01); C12N 5/0797 (2010.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0623 (2013.01); C12N 15/85 (2013.01); C12N 2500/14 (2013.01); C12N 2501/40 (2013.01); C12N 2501/405 (2013.01); C12N 2501/998 (2013.01); C12N 2506/00 (2013.01); C12N 2510/00 (2013.01);
Abstract

The present invention provides a neural stem cell having increased passage ability and a method for manufacturing a neural stem cell having increased passage ability. A neural stem cell in which the N-type calcium channel gene is knocked out or the influx of Ca2+ via the N-type calcium channel is substantially absent can be passaged for at least 4 generations and maintains the differentiation potential into a nerve cell even after passage for 4 generations.

Find Patent Forward Citations

Miyamoto, Norimasa. (2017). Neural stem cell having increased passage ability, method for manufacturing neural stem cell having said increased passage abiility, and method for culturing neural stem cells for increasing passage ability of neural stem cells (U.S. Patent No. 9574176). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9574176

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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