The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 21, 2017
Filed:
Dec. 01, 2011
Applicants:
Joseph Itskovitz-eldor, Haifa, IL;
Daniel Aberdam, Nice, FR;
Ruby Shalom-feuerstein, Binyamina, IL;
Inventors:
Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C12N 5/02 (2006.01); C12N 5/08 (2006.01); C07K 1/00 (2006.01); G01N 33/567 (2006.01); C12N 5/079 (2010.01); G01N 33/53 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0062 (2013.01); C12N 5/0621 (2013.01); C12N 2501/11 (2013.01); C12N 2501/155 (2013.01); C12N 2501/33 (2013.01); C12N 2502/085 (2013.01); C12N 2502/1323 (2013.01); C12N 2506/02 (2013.01); C12N 2506/45 (2013.01); C12N 2533/54 (2013.01); C12N 2533/90 (2013.01); G01N 33/53 (2013.01);
Abstract
A method of generating a population of corneal epithelial cells is disclosed. The method comprises culturing human pluripotent stem cells in corneal fibroblast-conditioned medium on a solid surface comprising an extracellular matrix component thereby generating the population of corneal epithelial cells. Isolated cell populations and corneal tissues are also disclosed, as well as uses thereof.