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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9574016 B1

PDFFull Text
Expired
Date of Patent:
Feb. 21, 2017

Filed:

Nov. 12, 2014

Complex of bi-specific antibody and digoxigenin conjugated to a therapeutic or diagnostic agent

Applicant:

Hoffmann-la Roche Inc., Little Falls, NJ (US);

Inventors:

Ulrich Brinkmann, Weilheim, DE;

Rebecca Croasdale, Antdorf, DE;

Wilma Lau, Munich, DE;

Guy Georges, Habach, DE;

Alexander Haas, Munich, DE;

Eike Hoffmann, Seefeld, DE;

Silke Metz, Bad Toelz, DE;

Olaf Mundigl, Weilheim, DE;

Werner Scheuer, Penzberg, DE;

Jan Olaf Stracke, Munich, DE;

Assignee:

Hoffmann-La Roche Inc., Little Falls, NJ (US);

Attorney:
Primary Examiner:

Jessica H Roark

Int. Cl.
CPC ...
C07K 16/44 (2006.01); A61K 31/704 (2006.01); A61K 39/395 (2006.01); A61K 47/48 (2006.01); B82Y 5/00 (2011.01); C07K 16/28 (2006.01); C07K 16/32 (2006.01); C12N 15/11 (2006.01); C12N 15/113 (2010.01); A61K 49/00 (2006.01); C07K 16/30 (2006.01); C12Q 1/68 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/44 (2013.01); A61K 31/704 (2013.01); A61K 39/39533 (2013.01); A61K 47/48676 (2013.01); A61K 47/48746 (2013.01); A61K 49/0058 (2013.01); B82Y 5/00 (2013.01); C07K 16/2803 (2013.01); C07K 16/2863 (2013.01); C07K 16/2896 (2013.01); C07K 16/30 (2013.01); C07K 16/32 (2013.01); C12N 15/111 (2013.01); C12N 15/1138 (2013.01); C12Q 1/6886 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/51 (2013.01); C07K 2317/55 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/622 (2013.01); C07K 2317/77 (2013.01); C07K 2317/92 (2013.01); C07K 2319/30 (2013.01); C12N 2310/14 (2013.01); C12N 2310/3513 (2013.01); C12N 2320/32 (2013.01); C12Q 2600/112 (2013.01);
Abstract

The present invention relates to complexes of a) bi-specific antibodies and antibody fragments against a target protein and b) a digoxigenin conjugated to a therapeutic or diagnostic agent, methods for their production, their use as a delivery platform for therapeutic or diagnostic agents, pharmaceutical compositions containing said antibodies, and uses thereof.

Find Patent Forward Citations

Brinkmann, Ulrich. (2017). Complex of bi-specific antibody and digoxigenin conjugated to a therapeutic or diagnostic agent (U.S. Patent No. 9574016). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9574016

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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