The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 21, 2017
Filed:
Jul. 05, 2012
Applicants:
Dawei LI, Shanghai, CN;
Zhenghua Wu, Shanghai, CN;
Hao Guo, Shanghai, CN;
Qi Zhu, Shanghai, CN;
Dhahiri S. Mashausi, Shanghai, CN;
Inventors:
Dawei Li, Shanghai, CN;
Zhenghua Wu, Shanghai, CN;
Hao Guo, Shanghai, CN;
Qi Zhu, Shanghai, CN;
Dhahiri S. Mashausi, Shanghai, CN;
Assignees:
Sanofi (China) Investment Co., Ltd. Shanghai Branch, Shanghai, CN;
Shanghai Jiao Tong University, Shanghai, CN;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/40 (2006.01); A61K 39/395 (2006.01); C12P 21/08 (2006.01); A61K 45/06 (2006.01); C07K 16/22 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/40 (2013.01); A61K 39/3955 (2013.01); A61K 45/06 (2013.01); C07K 16/22 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/34 (2013.01); C07K 2317/73 (2013.01); C12N 2510/02 (2013.01);
Abstract
Disclosed is an AGR2 blocking monoclonal antibody, and in particular, a humanized monoclonal antibody for blocking AGR2. Also disclosed is a pharmaceutical composition containing the antibody and a method for preparing the same, and a use of the antibody in blocking tumor growth and metastasis.