The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 21, 2017
Filed:
Dec. 28, 2011
Applicants:
Yoshimitsu Takakura, Oyama, JP;
Naomi Oka, Iwata, JP;
Inventors:
Yoshimitsu Takakura, Oyama, JP;
Naomi Oka, Iwata, JP;
Assignee:
JAPAN TOBACCO INC., Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C07K 1/00 (2006.01); C07K 14/00 (2006.01); A23J 1/18 (2006.01); A23J 1/00 (2006.01); C12N 15/00 (2006.01); C07K 14/37 (2006.01); C07K 14/375 (2006.01); G01N 33/53 (2006.01); C07K 14/465 (2006.01);
U.S. Cl.
CPC ...
C07K 14/37 (2013.01); C07K 14/375 (2013.01); C07K 14/465 (2013.01); G01N 33/53 (2013.01);
Abstract
The present invention provides modified tamabidin 2, which is a modified biotin-binding protein comprising an amino acid sequence represented by SEQ ID NO: 2, an amino acid sequence having one or more amino acid mutations in the amino acid sequence of SEQ ID NO: 2, or an amino acid sequence having an identity of not less than 80% to the amino acid sequence of SEQ ID NO: 2 and having biotin-binding activity, wherein an asparagine residue at position 115 of SEQ ID NO: 2 is replaced with cysteine. The modified biotin-binding protein has remarkable heat resistance.