The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 21, 2017

Filed:

Feb. 07, 2014
Applicant:

Aurobindo Pharma Ltd, Hyderabad, IN;

Inventors:

Shankar Reddy Budidet, Hyderabad, IN;

Nageshwar Dussa, Hyderabad, IN;

Gowrisankar Rao Kaki, Hyderabad, IN;

Srinivasa Rao Yatcherla, Hyderabad, IN;

Jagan Mohan Reddy Sanapureddy, Hyderabad, IN;

Subba Reddy Danda, Hyderabad, IN;

Srinivasachary Katuroju, Hyderabad, IN;

Sivakumaran Meenakshisunderam, Hyderabad, IN;

Assignee:

Aurobindo Pharma Ltd, Hyderabad, IN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 498/14 (2006.01); C07C 213/08 (2006.01); C07C 215/08 (2006.01); C07C 213/02 (2006.01); C07C 213/10 (2006.01); C07C 59/255 (2006.01);
U.S. Cl.
CPC ...
C07D 498/14 (2013.01); C07C 59/255 (2013.01); C07C 213/02 (2013.01); C07C 213/08 (2013.01); C07C 213/10 (2013.01); C07C 215/08 (2013.01);
Abstract

The present invention provides (R)-3-Amino-1-butanol (D)-tartarate (IIb); process for its preparation and its conversion to Dolutegravir. The present invention also provides an improved process for the preparation of Dolutegravir (I) or pharmaceutically acceptable salts wherein compound (XVI) is reacted with an optically active acid addition salt of (R)-3-amino-1-butanol (IIa).


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