The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 21, 2017

Filed:

Jul. 14, 2014
Applicants:

Asitha Abeywardane, Danbury, CT (US);

John Broadwater, Southbury, CT (US);

Steven Richard Brunette, New Milford, CT (US);

Thomas Martin Kirrane, Jr., Middlebury, CT (US);

Hossein Razavi, Danbury, CT (US);

Robert Sibley, North Haven, CT (US);

Lana Louise Smith Keenan, Poughquag, NY (US);

Qiang Zhang, Ridgefield, CT (US);

Inventors:

Asitha Abeywardane, Danbury, CT (US);

John Broadwater, Southbury, CT (US);

Steven Richard Brunette, New Milford, CT (US);

Thomas Martin Kirrane, Jr., Middlebury, CT (US);

Hossein Razavi, Danbury, CT (US);

Robert Sibley, North Haven, CT (US);

Lana Louise Smith Keenan, Poughquag, NY (US);

Qiang Zhang, Ridgefield, CT (US);

Assignee:

Boehringer Ingelheim International GmbH, Ingelheim am Rhein, DE;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/08 (2006.01); C07D 401/14 (2006.01); A61K 31/4439 (2006.01); A61K 31/496 (2006.01); A61K 31/4709 (2006.01); C07D 403/14 (2006.01); A61K 31/506 (2006.01); C07D 413/14 (2006.01); A61K 31/4995 (2006.01); A61K 31/551 (2006.01); C07D 405/14 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 487/08 (2013.01); A61K 31/4439 (2013.01); A61K 31/4709 (2013.01); A61K 31/496 (2013.01); A61K 31/4995 (2013.01); A61K 31/506 (2013.01); A61K 31/551 (2013.01); C07D 401/14 (2013.01); C07D 403/14 (2013.01); C07D 405/14 (2013.01); C07D 413/14 (2013.01); C07D 471/04 (2013.01);
Abstract

The present invention relates to aryl pyrazoles, and pharmaceutically acceptable salts thereof. The aryl pyrazoles of the present invention are useful as inhibitors of leukotriene Ahydrolase (LTAH) and treating LTAH related disorders. The present invention also relates to pharmaceutical compositions comprising the aryl pyrazoles of the present invention, methods of using these compounds in the treatment of various diseases and disorders, and processes for preparing these compounds.


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